Colonized, critically colonized and infected wounds: differentiation using clinical and microbiological and morphological methods of investigation

Objective . To analyze the clinical and microbiological morphological features of wounds different duration, allowing to differentiate stages infectious process determine recommendations for further tactics preoperative preparation. Materials methods Clinical assessment state acute chronic in 313 patients was performed. Results Colonized were characterized by presence pathological signs (atrophy, cicatricial changes) fine-grained granulations, frequency which increased from 38.5% lasting 22–28 days up 85.1% more than 2 months (χ2 = 14.0 ; p=0.003). Infected often detected at terms (24.6%, vs 3.9% old, χ2=40.51; p<0.001). Critically colonized made with coarse-grained granulations all wound existence (from 21.6 32.8%). The analysis biopsy specimens revealed initial proliferation disorders 22-28 day wounds, justifies need classify them as chronic. Second phase reparation failure cases wounds; severity purulent inflammation depending on stage process. Conclusion Differentiation using research is necessary determination indications use local debridement systemic antibiotic therapy preparation plastic closure.